Intan Technologies, LLC: low-noise amplifier microchips for electrophysiology, EKG, EMG, EEG, ECoG, and neural recording headstages and bio instrumentation
ECG/EKG signal recorded with Ag/AgCl electrodes on the chest. The amplifiers were configured with a lower cutoff frequency of 0.1 Hz and an upper cutoff frequency of 100 Hz.
EMG signal recorded with Ag/AgCl electrodes over bicep during two brief muscle contractions. The amplifiers were configured with a lower cutoff frequency of 10 Hz and an upper cutoff frequency of 1 kHz.
EEG signal with 10-Hz alpha waves recorded from occipital region (O2) with reference at Cz. Subject's eyes were closed initially, then opened at time zero, suppressing the alpha waves. The amplifiers were configured with a lower cutoff frequency of 1 Hz and an upper cutoff frequency of 100 Hz.
Several time-aligned cortical action potentials recorded extracellularly using a silicon microelectrode array. The amplifiers were configured with a lower cutoff frequency of 1 Hz and an upper cutoff frequency of 10 kHz.
Typical electrode-referred amplifier noise floor for RHA2000 amplifier with grounded input. The amplifier was configured with a lower cutoff frequency of 0.1 Hz and an upper cutoff frequency of 10 kHz.
Example signals acquired with RHA2000 chips
Here are some real electrophysiological signals obtained using RHA2000 series amplifier chips and standard electrodes: electrocardiograms (ECG/EKG), electromyograms (EMG), electroencephalograms (EEG), and neural action potentials. A typical noise floor for an RHA2000 amplifier is also shown.