RHA Electrophysiology Amplifier Chips

Introduced in 2010, RHA2000 amplifier chips are low-power microchips that contain 16 or 32 low-noise amplifiers for electrophysiology monitoring and recording applications. RHA2000 series chips are available in standard QFN surface-mount packages for solder assembly on printed circuit boards, and are also available in bare die form for advanced chip-on-board assembly.

The RHA2000 chips have multiplexed analog outputs, so an external ADC must be added. Our newer RHD2000 amplifier chips, introduced in 2012, incorporate an on-chip ADC as well as additional functionality and are recommended for new designs.

RHA2000 Family

  • RHA2116 16-channel amplifier chip with unipolar inputs and common reference
  • RHA2216 16-channel amplifier chip with bipolar (differential) inputs
  • RHA2132 32-channel amplifier chip with unipolar inputs and common reference

Features

  • Fully integrated electrophysiology amplifiers; no off-chip filter capacitors required
  • On-chip analog multiplexer allows many amplifiers to share one external ADC
  • Low noise floor: 2 μV rms typical
  • Upper cutoff frequency set by external resistor; configurable from 10 Hz to 20 kHz
  • Lower cutoff frequency set by external resistor; configurable from 0.02 Hz to 1000 Hz
  • In situ electrode impedance measurement capability with additional external components

Applications

  • Miniaturized multi-channel headstages for neural recording
  • Low-power wireless headstages or backpacks for electrophysiology experiments
  • "Smart Petri dish" in vitro recording systems
  • Simultaneous recording of action potentials and local field potentials (LFPs) from microelectrodes