Intan Technologies, LLC: low-noise amplifier microchips for electrophysiology, EKG, EMG, EEG, ECoG, and neural recording headstages and bio instrumentation

Intan Stimulation / Recording Controller
The 128ch Intan Stimulation / Recording Controller shown with four stimulation / amplifier headstages connected with red Stim SPI interface cables. The controller unit also has digital and analog I/O jacks. (Click for larger image and see detailed photos below.)

Main Documentation:

Intan Stimulation/Recording Controller user guide

RHS2000 digital stimulator / amplifier chips

See biological signals acquired using Intan Stimulation/Recording Controller

I/O Expander webpage

Supporting Documents:

RHS2000 USB/FPGA interface: RhythmStim webpage, datasheet

Pricing information

Intan Recording Stimulation / Controller front panel
Intan 128ch Stimulation / Recording Controller front panel: (Click for larger image.)

Stimulation / Recording Controller rear panel
Intan 128ch Stimulation / Recording Controller rear panel: (Click for larger image.)

16ch stim / amplifier headstage

16-channel stim/record headstage. An Intan RHS2116 16-channel digital stimulator /amplifier chip forms the heart of the headstage. Click for full-sized image.

32ch stim / amplifier headstage

32-channel stim/record headstage. A second 16-channel RHS2116 chip is mounted on the bottom side of the board. Click for full-sized image.

Intan Stimulation / Recording Controller

The Intan Technologies Stimulation/Recording System is a modular family of components based on the RHS2000 series of digital stimulator/ amplifier chips that allows users to perform electrical stimulation and recording across as many as 128 channels using small, affordable hardware and free, open-source software.

Any channel can independently source and sink currents from 10 nA to 2.55 mA over a +/-9V compliance range. Biphasic and triphasic current pulses are generated with timing resolution as fine as 33 microseconds. Stimulation pulses may be independent or coordinated across channels, and maybe be triggered by digital inputs or keypresses.

Integrated amplifiers have characteristics identical to Intan's RHD2000 extracellular recording chips, with new circuitry added to recover quickly from stimulation artifacts.

The Intan 128ch Stimulation/Recording Controller (Part #M4200) connects to a host computer via a standard USB connection. Small stim/ record headstages connect to the Stimulation / Recording Controller via thin, flexible Stim SPI interface cables that may be daisy-chained to form long, robust connections. Each headstage port has independent ground isolation to eliminate ground loop noise.

A 16-channel stim/record headstage (Part #M4016) and 32-channel stim/ record headstage (Part #M4032) are available (see photos below). Stim SPI interface cables are available in 3-ft (0.9 meter) lengths (Part #M3203) and 6-ft (1.8 meter) lengths (Part #M3206).

Included software controls the operation of the stimulators and amplifiers, and streams data to the screen and to disk in real time at user-selected sampling rates of 20, 25, or 30 kS/s. The software allows users to select amplifier bandwidths, measure electrode impedances, and select between a hardware reference or digital re-referencing to a selected amplifier channel.

The Intan Stimulation/Recording Controller has two analog input and output ports with +/-10V range and two digital input and output ports. Analog and digital inputs are recorded in synchrony with amplifier waveforms and may be used to trigger stimulation sequences or start recording sessions. Analog outputs may be configured to monitor selected amplifier channels. An audio output jack facilitates real-time monitoring of any two selected amplifier signals. Digital outputs can perform low-latency threshold-based spike detection.

An optional I/O Expander (part #E6500) may be added to the Stimulation/Recording Controller to increase the total number of auxiliary ports to 8 analog inputs, 8 analog outputs, 16 digital inputs, and 16 digital outputs.

The Stimulation/Recording Controller may be mounted in a standard 19" rack (1U) or operated from a bench top.

Note: The Intan RHD2000 recording-only headstages and SPI cables will not work with the Stimulation/Recording Controller. The stim/record headstages require additional voltages and control signals which necessitates the use of different interface cables, connectors, and communication protocols.

See the Intan Stimulation/Recording Controller User Guide for more information on the hardware and software.

Here is the compiled version 1.05 Intan Stimulation/Recording Controller software for Windows and Mac (updated 14 August 2018). This software can be run without a Stimulation/Recording Controller; it will generate synthetic neural data for demonstration purposes if no Controller is connected. For USB drivers and source code, visit our downloads page. Saved data can be loaded into MATLAB or Python.

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